With chronic systemic exposure, cobalt accumulates in tissue, again primarily the liver and kidney, and the cobalt level will be elevated in the serum, whole blood, and urine[9]. Recent studies indicate that a blood level of cobalt over 1.8 ng/mL and chromium over 1.0 ng/mL are “elevated” and require further investigation, especially if accompanied by a new onset of hip pain. Cobalt is a component of vitamin B12, which supports the production of red blood cells. Lab tests showed high levels of cobalt and chromium in the patient’s blood. Specialized blood tests can be used to detect levels of these toxic metals in ASR Hip Replacement patients. Cobalt is a naturally occurring element in the earth's crust. Cobalt is a naturally occurring element in the earth's crust. The following stratification applies to chromium or cobalt as individual analytes, not to the combined total. Cobalt salts are used in the glass and pigment industry. Previously, serum samples were collected and used to monitor patients with metal-on-metal implants, but serum can easily be contaminated during the harvesting and separation of the serum from the cellular blood … Very small amounts are needed for animals and humans to stay healthy. It is a very small part of our environment. Chromium and cobalt blood tests are used to monitor exposure to these elements. Normal chromium levels are between 10 and 200 nmol/L, but the patient’s chromium levels were at 595 nmol/L. These questions usually arise after clients get blood work done and the test reveals abnormally high metal levels. Cobalt poisoning can occur when you are exposed to large amounts of it. If you are reading this article, you probably already know that cobalt and chromium are two metals used in the construction of most metal-on-metal (MoM) artificial hip systems. Very small amounts are needed for animals and humans to stay healthy. It is a very small part of our environment. Cobalt poisoning can occur when you are exposed to large amounts of it. Normal cobalt levels are between 0 and 20 nmol/L, but the patient’s cobalt levels were at 757 nmol/L. Both of these elements are naturally occurring and widely distributed in the environment. In some cases, patients with DePuy ASR implants have been found with 100 times the normal levels chromium and cobalt in their bodies. Following cessation of the chronic exposure, the concentration of cobalt decreases by 51±21% and 66±29% in the blood … In this article we discuss the health risks that are related to chronically elevated blood cobalt concentrations induced by abnormal wear and corrosion of the MoM prosthesis. • Low risk group: <3.0 ng/mL • Moderate risk group: 3.0−10.0 ng/mL • High risk group: >10.0 ng/mL Specimens should not be collected for at least 96 hours after receiving iodine or gadolinium contrast media because they … Cobalt is a component of vitamin B12, which supports the production of red blood cells. Blood should not be drawn into plastic syringes with black rubber plunger seals because they contain high concentrations of both cobalt and chromium. COS : Cobalt is rare but widely distributed in the environment, used in the manufacture of hard alloys with high melting points and resistance to oxidation; cobalt alloys are used in manufacture of some artificial joint prosthesis devices. 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